Bam!
I performed a pre-flight on our Cessna 182 and all was well. Linda arrived, we loaded the groceries into the back seat and launched on an IFR plan to Page. We left Chino, California, at about 2 pm. Just as we pulled out of the LA Basin and leveled off at 10,000 feet, configured the mixture and prop and set the autopilot, BAM! I lost a cylinder.